Muscle Relaxers: Methocarbamol vs Cyclobenzaprine

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others. Other drugs may interact with cyclobenzaprine, including prescription and over-the-counter medicines, vitamins, and herbal products.

Here are examples of other drugs that may interact with tizanidine and cyclobenzaprine. Generally, the brand-name drugs are more expensive than the generics. Between the generics, tizanidine may be slightly more expensive than cyclobenzaprine.

• The condition can also be caused by damage to the muscle fibers directly, causing them to break down and release their contents into the blood.
• Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. phenobarbital, phenytoin).
• This document does not contain all possible drug interactions.
• Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepr[7]essants.
• The data revealed the presence of gabapentin alongside deadly opioids such as heroin and fentanyl.

With either drug, an allergic reaction is rare but possible. Serotonin syndrome, a life-threatening condition due to serotonin buildup, is also possible. Ask your pharmacist any questions you have about refilling your prescription. If you are not able to swallow the extended-release capsule whole, mix the contents of the capsule with applesauce. After you eat the mixture, take a drink, and swish and swallow to make sure that you have received all the medication. If you cannot swallow the capsule whole, you may open the capsule and sprinkle the contents over one tablespoon of applesauce.

Clinical monitoring

This combination can cause extreme drowsiness and respiratory depression, but many people that abuse Flexeril will mix the substances anyway simply to increase the intoxication experienced. Cyclobenzaprine is a prescription drug used short-term to treat muscle spasms. The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly). The elderly may also be more at risk for CNS adverse events such as hallucinations and confusion, cardiac events resulting in falls or other sequelae, drug-drug and drug-disease interactions. For these reasons, in the elderly, cyclobenzaprine should be used only if clearly needed. In such patients FLEXERIL should be initiated with a 5 mg dose and titrated slowly upward.

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Your healthcare provider and/or pharmacist will give you specific instructions on how to take the medication. Spasticity is a disruption in muscle movement patterns that causes certain muscles to contract all at once when you try to move or even at rest. It’s usually caused by damage to nerve pathways within your brain or spinal cord that control movement and stretch reflexes.

Side effects

You should have regular appointments with your healthcare provider when taking a muscle relaxant to assess how well it’s working. If you feel that you’re dependent on carisoprodol or diazepam or your prescribed dosage isn’t helping to manage your symptoms, don’t take more than your recommended dosage. In general, antispastic medications act on your spinal cord or skeletal muscle directly to improve muscle tightness (hypertonicity) and involuntary spasms. Health insurance plans usually cover the generic forms of both drugs without prior authorization. In many cases, insurance companies will require a prior authorization for Zanaflex or Amrix (a current brand name for extended-release cyclobenzaprine).

If they’re more severe or don’t go away, talk with your doctor or pharmacist. Drowsiness, dizziness, dry mouth, constipation, or tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Using Flexeril with other drugs that make you drowsy can worsen this effect.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects. Since overdosage is often deliberate, patients may attempt suicide by other means during the recovery phase. FLEXERIL may enhance the effects of alcohol, barbiturates, and other CNS depressants.

What is the difference between cyclobenzaprine and methocarbamol?

Less frequent dosing should be considered for hepatically impaired or elderly patients (see PRECAUTIONS, Impaired Hepatic Function, and Use in the Elderly). OXFORD TEXTBOOK OF Clinical pharmacology and drug therapy, 3rd edition. Was this just social and broadcast media hysteria or is this based on a real abuse phenomenon? As it turns out, after my initial scratch of the surface, there was a lot for me to uncover about the truth behind these gabapentin warnings. Muscle relaxers can cause more serious side effects like fainting and blurred vision.

Like almost all FDA-approved medications, when prescribed responsibly and taken as prescribed, gabapentin can offer great relief to those with these conditions. However, we all know that we live in a world in which not every patient takes medications as prescribed. Well, many prescription and non-prescription drugs taken in flexeril.live excessive amounts may cause death, even such innocuous drugs as aspirin and acetaminophen. Further review of the literature revealed yet another report of fatality by overdose, which was published the International Journal of Legal Medicine in 2015. Gabapentin is an anti-seizure drug that is also prescribed for nerve pain.